My research is in machine learning/data mining and natural language processing, with an emphasis on applications in health informatics.
For example, one of my major ongoing research aims concerns optimizing the processes of evidence-based medicine using novel natural language processing and machine learning methods. The aim is to reduce the (human) workload involved in conducting systematic reviews (i.e., making sense of the biomedical literature), so that we can realize the aim of evidence-based care in an era of information overload. An ongoing project in this direction is RobotReviewer.
More broadly, I am interested in core machine learning and natural language processing issues: e.g., structured and unstructured classiﬁcation techniques; neural models; semi-supervised learning methods; learning from imbalanced data; and learning from alternative forms of supervision. I tend to be most excited by interdisciplinary research that motivates technical questions by way of interesting applications.
Ryan Bridges, Jette Henderson, Joyce Ho, Byron C. Wallace and Joydeep Ghosh. Automated Verification of Phenotypes using PubMed Methods and Applications for Healthcare Analytics (MAHA) at ACM BCB; 2016.
An T. Nguyen, Matthew Halpern, Byron C. Wallace and Matthew Lease. Probabilistic Modeling for Crowdsourcing Partially-Subjective Ratings AAAI HCOMP; 2016.
Ye Zhang, Md Mustafizur Rahman, Alex Braylan, Brandon Dang, Heng-Lu Chang, Henna Kim, Quinten McNamara, Aaron Angert, Edward Banner, Vivek Khetan, Tyler McDonnell, An Thanh Nguyen, Dan Xu, Byron C. Wallace and Matthew Lease. Neural Information Retrieval: A Literature Review arxiv; 2016.
03/31/2017 Distinguished Clinical Research Informatics Paper Award at AMIA Joint Summits
Our paper, "PheKnow–Cloud: A Tool for Evaluating High-Throughput Phenotype Candidates using Online Medical Literature" was awarded the 2017 Distinguished Clinical Research Informatics Paper Award @ the AMIA joint summits. Joint work with Jette Henderson, Ryan Bridges, Joyce Ho and Joydeep Ghosh.
03/08/2017 SDM panel
I'll be serving on a panel at the annual Statistics and Data Mining (SDM) conference on Data mining, clinical medicine, and medical research: The current state and future of the nexus
09/13/2016 AHRQ grant funded
My AHRQ R03 grant, Hybrid Approaches to Optimizing Evidence Synthesis via Machine Learning and Crowdsourcing, has been selected for funding!
07/30/2016 Panelist @ IEEE ICHI
I'll be sitting on a panel on computational methods for evidence synthesis at IEEE ICHI 2016.