My research is in machine learning/data mining and natural language processing, with an emphasis on applications in health informatics.
For example, one of my major ongoing research aims concerns optimizing the processes of evidence-based medicine using novel natural language processing and machine learning methods. The aim is to reduce the (human) workload involved in conducting systematic reviews (i.e., making sense of the biomedical literature), so that we can realize the aim of evidence-based care in an era of information overload. An ongoing project in this direction is RobotReviewer. Here is an article written for a general audience about some of this work.
More broadly, I am interested in core machine learning and natural language processing issues: e.g., structured and unstructured classiﬁcation techniques; neural models; semi-supervised learning methods; learning from imbalanced data; and learning from alternative forms of supervision. I tend to be most excited by interdisciplinary research that motivates technical questions by way of interesting applications.
Matthew Lease, Gordon V. Cormack, An Thanh Nguyen, Thomas A. Trikalinos, and Byron C. Wallace. Systematic Review is e-Discovery in Doctor's Clothing Medical Information Retrieval (MedIR) Workshop at the 39th International ACM SIGIR Conference on Research and Development in Information Retrieval; 2016.
An T. Nguyen, Matthew Halpern, Byron C. Wallace and Matthew Lease. Probabilistic Modeling for Crowdsourcing Partially-Subjective Ratings AAAI HCOMP; 2016.
Silvio Amir, Glen Coppersmith, Paula Carvalho, Mário J. Silva and Byron C. Wallace. Quantifying Mental Health from Social Media with Neural User Embeddings Machine Learning in Health Care (MLHC); 2017.
07/12/2018 ARO grant
The Army Research Office (ARO) has has selected my proposal, "Neural Models for Text: Improving Efficiency, Interpretability and Accuracy" for funding.
07/02/2018 "Top Reviewer" @ ACL '18
I was recognized as a top reviewer for ACL 2018.
06/08/2018 SRSM Early Career Award
I have been selected as the recipient of the 2018 Early Career Award, from the Society for Research Synthesis Methods.
04/09/2018 Talks at upcoming local events: NEML, ODSC & NECHS
I'm excited to be giving invited talks at the New England Machine Learning day and Data Science Conference & Expo (ODSC East). I'll also be speaking on a panel at NorthEast Computational Health Summit (NECHS)