My research is in machine learning/data mining and natural language processing, with an emphasis on applications in health informatics.
For example, one of my major ongoing research aims concerns optimizing the processes of evidence-based medicine using novel natural language processing and machine learning methods. The aim is to reduce the (human) workload involved in conducting systematic reviews (i.e., making sense of the biomedical literature), so that we can realize the aim of evidence-based care in an era of information overload. An ongoing project in this direction is RobotReviewer. Here is an article written for a general audience about some of this work.
More broadly, I am interested in core machine learning and natural language processing issues: e.g., structured and unstructured classiﬁcation techniques; neural models; semi-supervised learning methods; learning from imbalanced data; and learning from alternative forms of supervision. I tend to be most excited by interdisciplinary research that motivates technical questions by way of interesting applications.
Elisa Ferracane, Iain Marshall, Byron C. Wallace and Katrin Erk. Leveraging coreference to identify arms in medical abstracts: An experimental study The International Workshop on Health Text Mining and Information Analysis (Co-Located with EMNLP 2016); 2016.
Zhiguo Yu, Elmer Bernstam, Trevor Cohen, Byron C Wallace and Todd R Johnson. Improving the Utility of MeSH terms Using the TopicalMeSH Representation Journal of Biomedical Informatics (JBI); 2016.
Iain J. Marshall, Joël Kuiper and Byron C. Wallace. RobotReviewer: Evaluation of a System for Automatically Assessing Bias in Clinical Trials Journal of the American Medical Informatics Association (JAMIA); 2015.
06/16/2017 Upcoming talks
I'll be giving a talk at Weill Cornell Medicine as part of their Machine Learning in Medicine series on 7/14. I'll also be giving a keynote at the 4th International Symposium on Systematic Review and Meta-Analysis of Laboratory Animal Studies in August.
03/31/2017 Distinguished Clinical Research Informatics Paper Award at AMIA Joint Summits
Our paper, "PheKnow–Cloud: A Tool for Evaluating High-Throughput Phenotype Candidates using Online Medical Literature" was awarded the 2017 Distinguished Clinical Research Informatics Paper Award @ the AMIA joint summits. Joint work with Jette Henderson, Ryan Bridges, Joyce Ho and Joydeep Ghosh.
03/08/2017 SDM panel
I'll be serving on a panel at the annual Statistics and Data Mining (SDM) conference on Data mining, clinical medicine, and medical research: The current state and future of the nexus
09/13/2016 AHRQ grant funded
My AHRQ R03 grant, Hybrid Approaches to Optimizing Evidence Synthesis via Machine Learning and Crowdsourcing, has been selected for funding!