Research overview

My research is in machine learning/data mining and natural language processing, with an emphasis on applications in health informatics.

For example, one of my major ongoing research aims concerns optimizing the processes of evidence-based medicine using novel natural language processing and machine learning methods. The aim is to reduce the (human) workload involved in conducting systematic reviews (i.e., making sense of the biomedical literature), so that we can realize the aim of evidence-based care in an era of information overload. An ongoing project in this direction is RobotReviewer. Here is an article written for a general audience about some of this work.

More broadly, I am interested in core machine learning and natural language processing issues: e.g., structured and unstructured classification techniques; neural models; semi-supervised learning methods; learning from imbalanced data; and learning from alternative forms of supervision. I tend to be most excited by interdisciplinary research that motivates technical questions by way of interesting applications.

A random sample of semi-recent publications

Byron C. Wallace, Marc J. Lajeunesse, George Dietz, Issa J. Dahabreh, Thomas A. Trikalinos, Christopher H. Schmid and Jessica Gurevitch. OpenMEE: Intuitive, open-source software for meta-analysis in ecology and evolutionary biology Methods in Ecology and Evolution; 2017.

An T. Nguyen, Matthew Halpern, Byron C. Wallace and Matthew Lease. Probabilistic Modeling for Crowdsourcing Partially-Subjective Ratings AAAI HCOMP; 2016.

Ryan Bridges, Jette Henderson, Joyce Ho, Byron C. Wallace and Joydeep Ghosh. Automated Verification of Phenotypes using PubMed Methods and Applications for Healthcare Analytics (MAHA) at ACM BCB; 2016.

News

04/09/2018 Talks at upcoming local events: NEML, ODSC & NECHS

I'm excited to be giving invited talks at the New England Machine Learning day and Data Science Conference & Expo (ODSC East). I'll also be speaking on a panel at NorthEast Computational Health Summit (NECHS)

02/05/2018 NSF CAREER

My NSF CAREER proposal, "Structured Scientific Evidence Extraction: Models and Corpora", has been selected for funding!

06/16/2017 Upcoming talks

I'll be giving a talk at Weill Cornell Medicine as part of their Machine Learning in Medicine series on 7/14. I'll also be giving a keynote at the 4th International Symposium on Systematic Review and Meta-Analysis of Laboratory Animal Studies in August.

03/31/2017 Distinguished Clinical Research Informatics Paper Award at AMIA Joint Summits

Our paper, "PheKnow–Cloud: A Tool for Evaluating High-Throughput Phenotype Candidates using Online Medical Literature" was awarded the 2017 Distinguished Clinical Research Informatics Paper Award @ the AMIA joint summits. Joint work with Jette Henderson, Ryan Bridges, Joyce Ho and Joydeep Ghosh.

Support

My work has been supported with grants from the National Institutes of Health, National Science Foundation, the Army Research Office, Seton hospital, Amazon and seed funds from Brown University.